Skincare Blog
Home Laser 101: How Often to Use It for Safe, Effective Results
Key Takeaways Frequency is Daily: The optimal, clinically-proven frequency for using your skin laser treatment machine is once a day. For potential enhancement, you may use it up to twice daily. Results Timeframe: Expect visible improvements after 8–12 weeks, with optimal, long-lasting results in about 90 days. Safety Protocol: Always ensure the treatment feels warm, not painful, and use the device on clean, dry skin to maximize the safe, non-invasive technology. Long-Term Strategy: Consistent daily use is essential to sustain collagen production and maintain your revitalized appearance over time. Investing in an at-home skin laser treatment machine is a proactive step toward maintaining youthful, resilient skin. For busy, data-driven individuals, this device represents more than just a gadget; it's a strategic tool for managing future skin health on a convenient, daily schedule. The key to transforming this investment into visible results isn’t raw power, it’s consistency. If you’ve purchased one of these advanced devices, a critical question arises: how often should you use it to see meaningful, lasting improvement without compromising the safety and integrity of your skin? The answer is rooted in the science of collagen, emphasizing a daily, non-invasive approach for optimal results. The Daily Commitment: Why Consistency Compounds Results When you invest in an advanced treatment, the goal of long-term improvement is measurable. Unlike surgical procedures or aggressive in-office lasers designed for immediate but intense trauma, at-home non-fractional laser technology is designed for gentle, cumulative energy delivery. The Science of Daily Activation Collagen is the structural protein that keeps your skin firm, smooth, and lifted. Starting in your mid-20s, the body’s production of collagen slows down. To counteract this, non-fractional lasers work by emitting a specific wavelength of 1450nm to safely heat the dermis (the collagen layer) below the pain threshold. This controlled heating subtly stimulates fibroblast cells, triggering the body's natural wound-healing response, which includes the rebuilding of new collagen. This process is analogous to exercising a muscle: daily, consistent effort yields far better long-term results than sporadic, intense sessions. Daily Use is Optimal: With a skin laser treatment machine like the NIRA Laser, daily use is strongly recommended for best results. The 90-Day Mark: Users typically begin to see visible improvements in skin texture, firmness, and fine line reduction after 8–12 weeks of consistent daily use, with optimal results visible at 90 days. Can You Use It More Than Once a Day? For those with a high-performance routine, a twice-daily treatment (morning and evening) is an option for potentially enhanced results. However, if your skin is particularly thin, start with once per day to avoid over-treating and drying out the skin. It is generally recommended to wait at least one minute before retreating an area and to avoid treating any area more than twice within a single hour. The Safety of Daily At-Home Laser Treatments A key concern for high-efficacy treatments is safety. Unlike older fractional or ablative laser procedures, which intentionally cause visible damage, downtime, redness, and peeling to force a healing response, modern non-fractional devices are designed to avoid this surface trauma entirely. The NIRA Laser uses FDA-cleared, non-fractional technology that targets the deep dermal layer while keeping the skin surface intact. This approach is proven safe for all skin types and tones without risk of hyperpigmentation or pain, making it suitable for consistent daily use. For personalization and comfort, the devices feature five comfort levels. The best practice is to set the device to a level where you feel warmth, but absolutely no pain. Best Practices for Maximizing Safety and Efficacy To ensure your investment delivers the best return, follow these fundamental guidelines: Start Low and Build Up: Begin with the lowest setting and gradually increase the intensity. Feeling warmth indicates the laser is working; feeling pain means the setting is too high. Ensure Full Contact: The laser needs to be flat against your clean, dry skin to deliver the precise energy pulse. Use on Clean Skin: Always start with a clean, dry face to ensure maximum laser energy absorption. Finish with Hydration: Post-treatment, apply supportive topicals like NIRA’s Moisture-Lock Hyaluronic Acid Serum and Youth Renewal Peptide Cream. These products lock in moisture and contain collagen-boosting ingredients to further enhance your results. The Power of Long-Term Maintenance For a proactive skincare enthusiast, the goal is long-term preservation, not just catching up with existing damage. Once you achieve your desired results at the 90-day mark, continuing a consistent daily routine is essential for long-term maintenance. Collagen naturally breaks down over time due to sun exposure, pollutants, and age. While results can be long-lasting, discontinuing use entirely means signs of aging will eventually return as natural collagen production slows again. Daily use ensures you consistently signal your skin to keep up the collagen production, safeguarding your skin’s firmness and youthful texture. Frequently Asked Questions Is an at-home laser as effective as a treatment at a dermatologist's office? At-home non-fractional lasers deliver lower power, but when used consistently over a long period, they can accumulate a high amount of total energy, delivering clinical-grade results comparable to professional treatments for reducing fine lines and improving texture, and are significantly more convenient and cost-effective. How long does a daily session take? A typical daily session using a device like the NIRA Pro Laser to treat the full face takes just minutes a day. The NIRA Precision Laser for targeted areas like crow’s feet and under eye wrinkles only takes two minutes. This short treatment time makes daily consistency highly manageable. Does daily use hurt my skin or increase sensitivity? No. Non-fractional laser technology is designed to gently heat the dermis below the pain threshold without damaging the skin's surface, eliminating the redness, peeling, and sensitivity associated with older, ablative treatments. You can customize the five comfort levels to your skin's sensitivity to ensure a painless experience. Will I lose my results if I stop using the laser? Collagen naturally degrades over time due to age and environmental factors. While many users maintain wrinkle reduction benefits for up to three months after stopping the treatment, the signs of aging may eventually reappear if daily support is discontinued. Should I use my serums before or after the laser treatment? For optimal results, use the laser on clean, dry skin to ensure maximum light absorption, and then apply your hydrating and collagen-boosting serums and creams immediately afterward. Choosing a consistent, science-backed routine is the smart approach to long-term skin health. By committing to a quick, daily routine with your skin laser treatment machine, you are actively investing in the preservation of your skin's firmness and texture, taking control of how you age.
Learn more
Laser Skincare in Your 30s & 40s: Prevent Wrinkles Before They Start
For a busy woman, skincare isn't a frivolous expense, it's a calculated self-investment. You're not looking for miracle creams; you're seeking proven, proactive strategies that fit your high-performance lifestyle and help you stay ahead of the aging curve. This means addressing the root cause of aging: collagen loss. While you may not see deep wrinkles yet, collagen production begins slowing in your mid-20s, and by age 40, your levels can drop by up to 30%. This guide is about utilizing smart, scientifically backed technology to preserve your skin's health now, so you can redefine how you age later. The Science of Prevention: Why Collagen Care Starts Now The foundation of firm, smooth, and resilient skin is collagen. As a structural protein, it acts as the scaffolding that keeps your complexion lifted and elastic. Here is the compelling truth for women in their 30s and 40s: The Decline Is Real: After age 20, your body produces about 1% less collagen every year. This gradual decline is why skin begins to feel thinner and loses its "bounce-back" feel. Hormones Accelerate Loss: For women approaching or in perimenopause (typically beginning in the 40s), a drop in estrogen accelerates the degradation of collagen and elastin. This can cause a rapid, noticeable shift in skin quality. Topicals Can Only Do So Much: While ingredients like Vitamin C, Retinol, and Peptides are crucial and act as "messengers" to support the surface and signal cells to work harder, most topical creams and supplements cannot penetrate the skin deeply enough to stimulate or rebuild collagen effectively at the dermal source. You need a solution that reaches the dermis, the deeper layer where collagen truly resides and is produced. The Game-Changer: Non-Fractional Anti-Aging Laser Technology This is where a medical-grade, at-home anti-aging laser is a true investment. It's the technology that bridges the gap between surface-level skincare and high-cost, in-office procedures NIRA Lasers employ patented non-fractional, non-ablative laser technology. This distinction is critical because it delivers: Precision and Depth: The laser emits a 1450 nm wavelength. This wavelength is specifically optimized to penetrate the epidermis (outer layer) without damage and be absorbed deep within the dermis. Collagen Activation: This targeted energy gently heats the dermis to a temperature threshold that stimulates the body’s natural healing response. This response includes activating the fibroblast cells to renew existing collagen and produce new collagen. No Pain, No Downtime: Unlike old fractional laser technology, which can be painful, risk-related to irritation and hyperpigmentation, and requires downtime. NIRA's non-fractional approach causes no damage to the skin's surface. This means you can use it daily without any redness or recovery period.NIRA is the only at-home laser that is FDA-cleared and clinically proven to reduce wrinkles by stimulating this natural collagen production. This is the scientific validation smart investors demand. NIRA: Clinically Proven, Effortlessly Integrated Smart technology should make life simpler, not more complicated. For busy individuals, efficiency is paramount. The NIRA laser system is designed for maximum impact with minimal time commitment: Fast, Daily Rituals: The NIRA Pro Laser treats the entire face in just two minutes a day. Even with the largest possible treatment area (full face, neck, chest, and hands) the longest treatment time is less than five minutes. Consistency is the Key to Long-Term Results: Much like saving for retirement, true anti-aging results are compounded over time with consistent, daily use. Most users begin seeing visible results, such as softer lines and improved firmness, within 60 to 90 days. The Long-Term Payoff: The consistent, gentle energy delivered daily by the NIRA laser offers a more cumulative and sustainable result than sporadic, high-intensity in-office treatments. Furthermore, 7 out of 10 users maintain their wrinkle reduction benefits for up to three months after stopping treatment. Powering Your Skincare Routine with Science To maximize your investment, combine the laser's deep dermal action with potent topical support. Moisture-Lock Hyaluronic Acid Serum: Apply this after your laser treatment. The serum contains both low and high molecular weight Hyaluronic Acid (HA). The Low Molecular Weight HA promotes cellular activation (fibroblasts) which aid in collagen production, while the High Molecular Weight HA locks in moisture and shields the skin barrier from pollutants. Youth Renewal Peptide Cream: This cream is formulated with a multi-peptide complex (Matrixyl 3000® and Argireline®) that is clinically proven to boost collagen production by 258% in just 60 days. Applying it as the final step in your routine enhances elasticity and provides dramatic wrinkle reduction. Key Takeaways This approach to wrinkle prevention is a calculated investment, leveraging clinical authority and daily efficiency to manage your skin's health proactively. The Investment Thesis: Skincare in your 30s and 40s must target the deeper dermis to actively stimulate new collagen production, addressing the natural decline (approximately 1% per year) that begins after age 20. The Non-Fractional Advantage: The core technology is a non-fractional, non-ablative laser that delivers a precise 1450 nm wavelength to the dermal layer. This patented method safely generates the heat needed for collagen renewal without damaging the skin's surface, ensuring the treatment is painless and requires zero downtime. Efficiency Drives Consistency: The device is engineered for a high-performance lifestyle, offering a full-face treatment in just two minutes a day. Consistent, daily application is the compounding factor that leads to visible results in 60 to 90 days. Clinically Proven Results: NIRA's technology is FDA-cleared and proven to reduce wrinkles. Pairing the laser with supportive topicals, like the Youth Renewal Peptide Cream, significantly enhances efficacy, as the cream's complex is clinically shown to boost collagen production by up to 258%. Frequently Asked Questions 1. Is this a painful treatment, and is there any recovery time (downtime)? No. The NIRA laser utilizes non-ablative technology, meaning it treats the lower dermal layer without wounding the skin's surface. This is a critical distinction from traditional or fractional lasers. The treatment is designed to be completely painless and requires zero downtime, allowing you to integrate it into your daily routine and immediately apply makeup or sun protection. 2. How quickly should I expect to see definitive wrinkle reduction results? Results are cumulative and depend on consistency. While initial changes may be subtle, most users report visible improvements in wrinkle reduction and overall skin firmness within 60 to 90 days of dedicated daily use. Think of this as a long-term investment: consistent, moderate stimulation yields sustainable results. 3. How does this non-fractional laser differ from high-end anti-aging creams? Most topical products contain molecules too large to penetrate the outer skin layer (the epidermis) effectively enough to influence structural collagen deep within the dermis. The laser, with its optimized 1450 nm wavelength, bypasses the epidermis to deliver targeted, activating heat energy directly to the dermal layer, making it far more effective at stimulating foundational collagen renewal than surface-level creams. 4. Is the device safe to use every single day? Yes. The NIRA laser's gentle, patented technology is specifically designed and FDA-cleared for daily use. Unlike more aggressive, high-intensity treatments that require long intervals between sessions, the daily application is key to continually stimulating the body’s natural collagen production mechanism, leading to compounded, long-term skin health. 5. Do the wrinkle reduction benefits last, or do I need to use it forever? The collagen that the device helps your body create is foundational and long-lasting. While continued periodic use is recommended for maintenance and ongoing prevention, clinical data shows that 7 out of 10 users maintain their wrinkle reduction benefits for up to three months after stopping regular treatment Invest in Your Skin’s Future: Look and Feel Your Best, Barefaced Your skin is an asset that deserves proactive management. Investing in the NIRA anti-aging laser is about gaining control over how you age. It's choosing a data-backed, non-invasive path to long-term skin health. By incorporating this powerful, two-minute, FDA-cleared technology into your daily routine, you are committing to proactive beauty. You move beyond simply reacting to wrinkles and move toward building a solid, resilient foundation that keeps your skin looking as vibrant and accomplished as you feel. Start now. The fastest path to long-term skin health is consistent, intelligent action.
Learn more
Your Ultimate Guide to At-Home Skincare Laser Treatment
Navigating life in your 40s and 50s comes with a well-earned sense of confidence and self-awareness. You’ve built a career, nurtured a family, and curated a life that reflects your values. This chapter isn’t about chasing youth; it’s about owning your story and showing up as the most vibrant version of yourself. As our bodies change, so does our skin, reflecting hormonal shifts and life’s rich experiences. For many of us, this means seeing more fine lines, a loss of firmness, and a desire to restore the skin’s natural radiance. The world of advanced skincare can feel overwhelming, but what if you could access professional-grade technology from the comfort of your own home? At-home skincare laser treatments are redefining the way we approach skin renewal, putting the power of dermatology right into your hands. This guide will walk you through how this innovative technology works and why it’s becoming an essential ritual for women who value evidence-backed beauty and visible results. Understanding At-Home Laser Technology For years, effective laser treatments were confined to dermatology clinics and med spas. The goal of these treatments has always been to address signs of aging at their source, deep within the skin’s layers. At-home skincare lasers operate on the same core principles, using focused light energy to create change where it matters most. NIRA’s technology, for example, was developed by laser industry experts to bring these professional-grade results home. Our devices use a patented, non-fractional laser to gently and safely heat the dermis, the layer of skin responsible for generating collagen. Collagen is the structural protein that gives skin its youthful firmness and elasticity. As we age, collagen production naturally declines, leading to common concerns like wrinkles and sagging skin. By creating a controlled and gentle warmth directly into the skin dermis, the laser signals your cells to ramp up their natural collagen production, effectively rebuilding your skin’s supportive structure from the inside out. The NIRA Difference: Clinical Confidence Without Compromise We understand that you’re discerning about the products you bring into your life. You’re knowledgeable about ingredients, you research before you buy, and you demand solutions that are both effective and safe. That’s why trust and transparency are at the core of everything we do. Here’s what sets NIRA’s approach to at-home laser treatment apart: FDA-Cleared and Clinically Proven: Safety and efficacy are non-negotiable. NIRA’s technology is FDA-Cleared and has been clinically proven to reduce fine lines and wrinkles. This isn’t about hope in a bottle; it’s about science you can rely on. A Comfortable, Gentle Experience: Many women, especially those with sensitive skin, worry about discomfort with advanced treatments. Our non-fractional laser technology works without damaging the skin’s surface, which means you won’t experience any pain, redness, or downtime. To further accommodate skin sensitivity, our lasers also feature five comfort levels. Designed for Your Busy Life: Your time is valuable. A skincare routine needs to fit seamlessly into your day, not complicate it. NIRA laser treatments are remarkably quick and easy, requiring just two to five minutes daily to achieve visible results. An Effortless Skincare Ritual for Visible Transformation Integrating an at-home laser treatment into your daily routine is simple. The key is consistency. With just a few minutes each day, you can achieve visibly firmer, more youthful-looking skin in about 90 days. We offer two devices designed to meet your specific skin renewal needs: NIRA Precision Laser: With a small precision tip, this device is perfect for targeting hard-to-treat areas. In just two minutes a day, you can address fine lines and wrinkles around the eyes and mouth. Users have reported a visible reduction in crow’s feet, a brighter under-eye area, and lifted, less hooded eyes. NIRA Pro Laser: For those seeking broader skin renewal, the NIRA Pro features a larger treatment tip to cover the full face, neck, chest, and even the back of your hands in minutes. It is the largest and fastest painless at-home laser available, making it an incredibly efficient tool for comprehensive skin rejuvenation. To enhance your results, follow your laser treatment with products designed to hydrate and nourish the skin. Our Moisture-Lock Hyaluronic Acid Serum deeply hydrates and amplifies moisture retention, while the Youth Renewal Peptide Cream uses a powerful multi-peptide complex to further support collagen production and dramatically reduce the appearance of wrinkles. Key Takeaways The NIRA approach is designed for the empowered woman who values visible, proven results without sacrificing convenience. Redefining Midlife Beauty: This phase of life is about owning your confidence and vitality, not chasing youth. The focus shifts to skin renewal and supporting the strength and radiance you already possess. Science-Backed Collagen Renewal: Unlike creams that only treat the surface, the NIRA device uses patented, non-fractional laser technology to deliver gentle heat directly to the dermis. This stimulates your body's natural production of collagen from the inside out, addressing the root cause of fine lines and loss of firmness. The Power of Clinical Proof: NIRA technology is FDA-Cleared and clinically proven to reduce the appearance of fine lines and wrinkles, providing the credible, evidence-backed efficacy discerning women demand. Effortless Integration: The treatment fits seamlessly into a busy life, requiring only two to five minutes daily with absolutely zero pain, redness, or downtime. This makes consistency easy to achieve. Visible Transformation: By committing to this quick, easy ritual, users can expect to see visibly firmer, smoother, and more youthful-looking skin in approximately 90 days. Frequently Asked Questions Do at-home skincare lasers actually work? Yes, when they utilize verified technology. NIRA's devices are FDA-Cleared and clinically proven to stimulate natural collagen production, which effectively reduces fine lines and wrinkles. This is not a superficial treatment; it uses focused light energy to initiate the skin’s own regenerative process deep within the dermis. The key is consistent, daily use, which our efficient 2–5 minute treatment supports. How does NIRA's non-fractional technology compare to intense professional laser treatments? Professional fractional lasers penetrate the skin deeply but create micro-wounds, leading to pain and necessary downtime. NIRA uses a non-fractional laser that delivers controlled, gentle heat to the collagen-producing layer of the dermis without damaging the skin's surface for the dermis itself. This difference means you get clinically validated collagen stimulation and visible wrinkle reduction without the pain, redness, or recovery time associated with clinic visits. Is the NIRA at-home laser painful to use, and is there any downtime? The NIRA laser treatment is designed to be painless, with no associated redness or downtime. Our non-fractional technology ensures the skin's surface is not damaged. The device features five comfort levels, allowing you to gradually adjust the intensity as your skin adapts, always maintaining a comfortable experience. You can easily complete your 2-5 minute ritual and continue immediately with your day. How quickly should I expect to see visible results after starting the NIRA skincare ritual? While the collagen renewal process begins immediately, visible results require consistency. Users typically see noticeable improvement in skin firmness and a reduction in fine lines in about 90 days of consistent daily use. Like any meaningful self-care investment, the transformation is a gradual, lasting process of renewal, not an overnight fix. What is the key difference between the NIRA Precision and the NIRA Pro laser? Both devices use the same proven non-fractional laser technology to stimulate collagen. The difference lies in the treatment area size: NIRA Precision Laser: Features a small, targeted tip, ideal for treating fine lines and wrinkles around the eyes (crow’s feet) and mouth. NIRA Pro Laser: Has a larger treatment tip, making it the fastest and largest painless at-home laser available for comprehensive treatment of the full face, neck, chest, and hands. Embrace the Glow of Confidence Choosing to invest in your skin is an act of empowerment. It’s about honoring the woman you are today while giving your skin the support it needs to look as vibrant as you feel. With at-home laser treatments, you no longer have to choose between professional-grade results and the convenience of your daily routine. You can have both. This is your time to focus on yourself, to celebrate every chapter, and to feel confident in the skin you’re in. A simple, science-backed ritual is all it takes to unlock a renewed sense of radiance.
Learn more
Non-Fractional Dynamic Treatment of Wrinkles with Low Power
TL;DR A 16-week at-home study of a low-power 1450 nm NIRA laser (67 completer, ages 35–65) showed statistically significant periorbital wrinkle reduction, with ~69% achieving ≥1 full Fitzpatrick Wrinkle Scale improvement and high user satisfaction. Blinded clinician reviews confirmed results, adverse events were mild (brief warmth/dryness/color changes), and many participants maintained improvements 2–3 months post-treatment. Action: Use the NIRA device daily per instructions for 16 weeks, photograph progress monthly, and reassess at 3 and 7 months. David Bean, Zilong Huang, Felix Feldchtein, Kayla Govoni, Dermal Photonics Corp. (NIRA Brand) January 20, 2019 OBJECTIVE AND BACKGROUND DATA: Non-ablative laser treatment has been shown to reduce the severity of wrinkles. These procedures are commonly done with relatively high power lasers by trained professionals. The purpose of this study is to evaluate the safety and efficacy of reducing wrinkles using a relatively low power, in-home laser procedure. MATERIALS AND METHODS: Sixty-seven participants with wrinkles between the ages of 35 and 65 completed the study meeting all protocol requirements. Participants administered treatment at home, once per day over 16 weeks (4 months). Self-report and clinician ratings of wrinkle severity were made each month for each participant. At the conclusion of the trial, participants rated their satisfaction with their results and the effectiveness of the product. Three clinicians, not involved in the study, reviewed photos of the trial and rated severity on a blinded and randomized basis. RESULTS: Wrinkle Analysis by the clinician and three blinded evaluators showed significant improvements in wrinkles. Most participants reported high levels of satisfaction and said they would recommend the product to a friend. No serious adverse effects were reported and most participants reported little to no pain. CONCLUSION: The laser treatment successfully provided improvement in wrinkles without significant side effects, such as pain and erythema, and with high satisfaction scores. Introduction Wrinkles are one of the most obvious signs of aging. Wrinkles typically first appear around the eyes and the effects of aging hinder a person’s confidence which can also lead to psychosocial abnormalities1. The “anti-aging” market is a multi-billion2 dollar industry, with millions of baby boomers hoping to reduce the appearance of growing fine lines and wrinkles2. As a person ages, several alterations occur in the skin’s internal factors. These include stiffening of skin and interaction of permanent muscle contraction, and gravity effect upon thinned, inelastic dermis resulting in wrinkles. In simpler terms, wrinkles are caused by the degradation and loss of the collagen volume in the skin. Collagen controls skin strength and elasticity. With limited exceptions such as RetinA and Tazorac used for fine lines, topical treatments have limited effects on wrinkles, since they cannot access the collagen layer. To rejuvenate the skin is to stop or reverse the aging effects of the skin. The injury of the skin and the subsequent wound healing response is one of the mechanisms that result in younger looking skin. The development of rejuvenation treatments for aged skin is booming, especially the area of laser-based techniques, consisting of ablative and non-ablative laser cosmetic surgery. An induced thermal trauma by laser therapy leads to stimulation of collagen synthesis. The result is skin thickening and tightening. There has been a great interest in lasers in plastic surgery and dermatology, particularly those with short recovery periods. However, the cost, side effects and recovery times of these treatments discourage many, if not most, people from purchasing laser treatments. Laser treatments work by heating the skin with the laser, and the light is absorbed by water in the dermal layer of the skin. High power non-ablative laser treatment has been effective, but often requires significant postoperative healing time and can result in pain, erythema, and scarring.3-4 Non-ablative lasers with wavelengths near 1450nm have been shown to reduce wrinkles with fewer side-effects. Unlike ablative laser resurfacing, which removes the epidermis, non-ablative laser treatment penetrates the epidermis and reacts with the upper dermis while leaving the epidermis fully intact without damage.5 1450nm light is at a local absorption spectrum peak of water that allows a penetration depth of about 500μm into the dermis, which is ideal for treating wrinkles. To minimize side-effects such as pain and erythema, fractional laser treatment is used on a small portion of the skin, typically about 10%, in a dot matrix format. Home lasers for wrinkles commonly use this approach which drives the local treated skin areas to cellular necrosis while maintaining a healthy non-ablated epidermis. The cells affected by the laser regenerate with the assistance of neighboring cells that are unaffected by the laser which support new skin formation and fast recovery. The treated areas typically experience localized pain and erythema as side effects that are tolerable to many users. However, these side effects can be a deterrent for this approach for many other users. Other non-ablative methods that are considered leading treatments for wrinkles include chemical peels, retinoids and other topical agents. However, the cost, side effects and down times of these treatments can be detrimental. Chemical peels can cause chemical reactions leading to a burning sensation and accompanied by erythema and scarring. Dermabrasion treats the epidermis layers of your skin, which can cause pain, scarring, erythema and skin irritation. Retinoid can cause dryness and peeling of the skin, but the effects have a shorter recovery period than all other treatments. The leading non-ablative treatments for wrinkles include Botox, fillers, and collagen injections. These treatment methods can lead to side effects and unwanted outcomes including unnatural facial appearance. The above discussion underscores the need for additional means to treat wrinkles. This study was conducted to assess the new Precision Protein Promotion (P3) technology from Dermal Photonics Corp. (NIRA Branded), which has the potential to treat periorbital wrinkles without pain and erythema. P3 technology works by dynamically driving the laser to increase the temperature of the dermis over the threshold for heat-shock-protein (HSP) generation of about 39C but short of the pain threshold of approximately 45C6-7. The laser accomplishes this by bulk heating the skin with a laser in a non-fraction uniform way, quickly at first, and then the laser dynamically lowers its fluence as it approaches 45C dermal temperature. Then, the laser provides a fluence to maintain the dermal temperature just below the pain threshold. Using this approach, the dermal cells are intended to be slightly stressed but not damaged. Since the cells are bulk heated for about a second above 39C, there is significant time for HSP generation. After the laser treatment is completed, it takes several seconds for the dermis to lower back to below 39C causing HSP generation for approximately 3 seconds in a 1 second treatment. The HSP generates a skin rejuvenation response that promotes new collagen formation and existing collagen remodeling 6-7. The effects of the treatment depend on the amount of energy delivered, which can be controlled by switching between power levels one through five, as well as the size of the treatment area, pulse duration, and the number of pulses. The laser treatment results in thermal injury to the dermis where the collagen is located5. This injury promotes regrowth and replenishment of healthy cells, thus decreasing the appearance of wrinkles. This study will evaluate the efficacy of the P3 approach using a relatively low power hand-held laser with a non-fractional 1450nm wavelength that is safe for use at home. The laser is contained in a handheld device and outputs a fluence between 2.5-3.0 J/cm2 which is a lower output utilized in professional trials that range between 7.0-20.0 J/cm2. The fluence used in this study is about the same as the home fractional laser studies done by Palomar Palovia and Tria Beauty Age Defying Laser. Materials and Methods Participant Criteria Inclusion criteria for all wrinkle participants included Fitzpatrick skin types I to IV and Fitzpatrick wrinkle scale grading of at least 3 on a scale of 1-9. Criteria for age ranged between 35 to 65 years old. Exclusion criteria included anyone pregnant or planning to be pregnant, undergoing fertility treatments, or nursing. Subjects that had laser treatments on the face within the last 4 weeks or Botox treatments within the study areas in the past 3 months were also excluded from the study. The last part of the exclusion criteria included subjects who were severely immunocompromised (such as may occur in AIDS, renal transplant regimens, immunosuppressed states consequent to malignancy or agents used rendering oncologic care, or in those who suffer from end stage renal disease), and subjects with psoriasis or lichen planus on the face. Participants were required to wear sunscreen whenever exposed to the sun, and they were and they were required to avoid applying wrinkle cream, using Botox or fillers, or undergoing other cosmetic procedures for the duration of the study. Participants had to be willing to take home the device and use the device consistently on a daily basis as well as following up in person every four weeks to be clinically evaluated. Participants After providing informed consent, 76 participants in the study met the protocol requirements under the supervision of Dr. David Greenstein, which lasted for a total of 7 months (28 weeks). 70 participants were female and 6 were male. Age ranged from 35 to 65 years old. The skin color as measured by Fitpatrick skin tone scale, is shown below for participants. Treatment Procedure Phase 1 V1: Initial visit before treatment V2: Visit 2 after 4 weeks of treatment V3: Visit 3 after 8 weeks of treatment V4: Visit 4 after 12 weeks of treatment V5: Visit 5 after 16 weeks of treatment (end of treatment period) Wrinkle participants conducted treatment with the NIRA skincare laser in the periorbital regions (areas around the eye only). The duration of this study was over the course of 7 months (28 weeks). The first phase of the study consisted of 4 months (16 weeks) of treatment and 5 clinician visits. Participants were required to make a clinician visit for their initial evaluation and to have their photographs taken (V1) before starting treatment. Following the initial visit (V1), participants were required to take home the NIRA device to start daily treatments. Participants were required to follow up with a clinician visit to be evaluated at the end of week 4 (V2), week 8 (V3), week 12 (V4) and week 16 (V5). At each subsequent visit, the laser was checked for proper operations and results were recorded in the clinical study log. Participants informed the clinician of any adverse reactions that occurred since the previous laser treatment. Participants were then asked to log into the NIRA web portal to review the data with the clinician staff. In addition, each participant was to remove all makeup, wash face with soap and water, dry face, and clean face with alcohol wipes to remove excess oils and moisture. Participants then performed the laser treatment without any assistance or advice, and would only have the Instructions for Use as a guide while performance was evaluated and documented by the clinician staff. Each visit the participant was evaluated and an assessment was made of the skin condition. The fifth clinician visit (V5) (week 16) completed the NIRA laser treatment phase of the study, and the participants returned the device. The last 3 months (12 weeks) of the study, participants were evaluated based on visual observations by the clinicians with no continued laser treatment. To ensure there were no adverse events, participants continued with their clinician visits at week 20 (V6), week 24 (V7), and week 28 (V8). The continued visits included the participants logging into their NIRA web portal and reviewing their data with clinician staff up through week 16 (V5). In addition, each participant was to remove any makeup, wash face with soap and water, dry face, and clean face with alcohol wipes to remove any excess oils and moisture. Then, photographs of the participant were taken. Lastly, participants were evaluated, and an assessment was made of their skin by the clinician. Figure 1: NIRA Laser Device used for treatment Laser Treatment Method The laser used, shown in figure 1, had a wavelength of 1450nm. The spot size of the pulse was 4mm x 4mm, each laser pulse lasted between 0.8 seconds and was made up of 5ms sub-pulses on a 70% to 80% duty cycle with dynamically modulated fluence to maintain the appropriate dermal temperature profile. Each participant was treated with 40-60 pulses per treatment around each eye (periorbital area). The laser provided a fluence of up to 3.3 J/cm2. The handheld device had a power operating range from 1 to 5 corresponding to energies of 2.5 to 3.0 J/cm2. The settings were adjusted as necessary by the subject for their comfort level. The subject was specifically given the protocol to set the laser level so they feel warmth without any pain. Treatment was performed on the periorbital areas of the participants. Two or three rows of treatments were performed to cover the treatment area around the eyes. Treatment was administered at home on a daily basis for the duration of 4 months (16 weeks). During the last 3 months post treatment phase of the study, participants were continuously evaluated to monitor any adverse results from treatment, and further pictures were taken to identify if improvements were maintained. Data Collection / Wrinkle Analysis The primary wrinkles data was in the form of high-resolution photographs that were taken during each visit by a professional photographer using a digital Nikon SLR camera under a consistent photography studio setup. The photography studio was set up in the office suite adjacent to the doctor’s office that housed the clinical study visits and evaluations. The lighting and photography settings were unchanged for the duration of the clinical study. The treatment evaluation consisted of an independent examination by each of three clinicians, scoring the participant based on scoring the participant visit photos shown in randomized order. The periorbital area of each participant was scored by the three independent clinicians using the Fitzpatrick Wrinkle Scale (FWS). Figure 2a: (Left) Photograph taken at V1 (stage 1) treatment. (Right) Photograph at the last treatment V8. There are fewer visible wrinkles, and the wrinkles that are still present were reduced in size and depth. Three independent evaluators completed two separate evaluations several weeks apart. The first evaluation scored the photographs of the subjects taken during the initial visit (V1) prior to any treatment, and during the 8th visit (V8) as shown in figure 2a; importantly, the photographs were in random order and evaluators were blinded to which photograph was V1 and which was V8. In the second independent evaluation, evaluators scored all visit photos using the same FWS as before. The photos shown to evaluators were in random order for visits V1, V4, V5, V6, V7, and V8. The photos were labeled A through F as shown below in Figure 2b. The null hypothesis of this test determined that the populations of the Fitzpatrick Skin types I-IV were normally distributed. The Sharpiro-Wilk test determined that the periorbital scores did not show a normal distribution, therefore per the protocol, a rank test was used to assess the statistical significance. The slight clinically significant difference is defined as a mean improvement in score across all subjects by one score or more from baseline as determined by the median of the three blinded evaluators. Figure 2b: Randomized blinded review setup. Effectiveness was determined by comparing within-patient change-from-baseline using the Fitzpatrick Wrinkle Scale (FWS) for wrinkles. Successful treatment was defined as an improvement in score by one or more from the baseline. Dennett’s adjusted p-value of greater than 0.0001 was considered to compare each week’s improvement to the baseline. The P value, or calculated probability, is the probability of finding the observed, or more extreme, results when the Page | 5 Confidential null hypothesis (H0) of a study question is true – the definition of ‘extreme’ depends on how the hypothesis is being tested. The result provided a more accurate value towards the culmination of the evaluation. Results Effects on wrinkles There were a total of 76 participants and 67 of the participants completed the study meeting all protocol requirements. The participants that were unable to comply with set instructions or fell below the Fitzpatrick scale of level 3 were considered drop outs described under the ruling of the protocol. 9 participants were withdrawn from the study for compliance reasons. Table 1.1 shows a per protocol analysis with the removal of participants for different protocol violations to compare the mean, median and p-value from the signed rank test (H0) that calculated the overall improvement in the appearance of wrinkles. A negative value indicates improvement. Successful treatment is defined as an improvement in score by one score or more from the baseline. No.Participants Mean Median P-value 76 -0.974 -1.00 <0.0001 72 -0.958 -1.00 <0.0001 69 -1.014 -1.00 <0.0001 67 -1.075 -1.00 <0.0001 Table 1.1: Shows the mean, median and p-value from the signed rank test (H0) that calculated the overall improvement in the appearance of wrinkles. A negative value indicates improvement. Successful treatment is defined as an improvement in median score by one score or more from the baseline. An improvement of at least one score was seen in 64.5% (49/76) of subjects on the overall wrinkle assessment. This is a statistically significant improvement and more than half of the subject’s showed improvement on overall assessment leading to the median being a one score improvement. With the removal of four subjects with no visit 8 (V8) per protocol violation, an improvement of at least one score was seen in 63.9% (46/72) of subjects on the overall wrinkle assessment. This result is a statistically significant improvement and the more than half the subject’s showed improvement on overall assessment leading to the median being a one score improvement. With the removal of four subjects with no visit 8 (V8) and three subjects that fell below level 3 on the Fitzpatrick scale per protocol violation, an improvement of at least one score was seen in 66.7% (46/69) of subjects on the overall wrinkle assessment. A statistically significant improvement was seen, and the mean improvement of the overall wrinkles assessment is higher than one score in addition to more than half of the subjects showing an improvement on the overall assessment leading to the median being a one score improvement. With the removal of four subjects with no visit 8 (V8) and three subjects that fell below the Fitzpatrick scale of level 3 and two subjects that smiled in their initial photo for the initial visit (causing an inaccurate wrinkle baseline) before starting treatment per protocol violation, an improvement of at least one score was seen in 68.7 (46/67) of subjects on overall wrinkle assessment. A statistically significant improvement was seen, and the mean improvement of overall wrinkles assessment is higher than one score in addition to more than half of the subjects showing an improvement on overall assessment leading to the median being a one score improvement. Figure 3: Shows the percentage of participants who saw full wrinkle scale improvements from 3 months to 7 months. Periorbital treatment met the predefined clinical and statistical endpoint with a median reduction of one unit in the Fitzpatrick Wrinkle Scale. As shown in figure 3, an improvement of at least one score was seen in 69% of subjects and 36% of subjects saw 2 full wrinkle scale improvements. 10% of subjects saw 3 full wrinkle scale improvements at 7 months on the overall periorbital facial wrinkles assessment. There was full-scale wrinkle improvement in as little as 3 months. 61% of users saw 1 full wrinkle scale unit improvement within 3 months and 12% of users saw 2 full wrinkle scale unit improvements within as little as 3 months. The three independently blinded professionals found that 81% of participants continued to see improvements in the appearance of wrinkles for at least 2 months after they stopped using the NIRA device, and 68% of participants continued to see improvements in the appearance of wrinkles for at least 3 months after they stopped using the NIRA device. Safety of the Participants This study evaluated the safety and efficacy of a low power laser with a 1450nm wavelength that is safe for at home use. The NIRA laser, shown in figure 1, allows people to treat themselves with the same technology as professionals at a substantially reduced cost. The effects of the treatment depend on the amount of energy delivered, which can be controlled by switching between power levels 1 through 5. Safety was assessed by evaluating types of severity, duration, resolution, and rates of adverse events, and their possible relationship to the laser treatments. No unanticipated or severe adverse events were reported. On a small minority of participants, adverse events that were reported included skin warmth and minor stinging, dryness, and temporary skin color changes where skin became darker in color but these were not unexpected. There was no data showing any adverse events due to skin type V or VI. Figure 4: Shows participants results from the satisfaction survey that include results from an addition study with acne participants Discussion A major endpoint of this study was achieved with the majority of participants achieving a reduction of at least 1 on the Fitzpatrick Wrinkle Scale. As seen in Figure 2, the photographs showed a number of visible wrinkle reductions in participants. The observations were confirmed by the blinded clinician’s analysis of the photographs. These results lead to further consideration of this handheld system as a successful adjunct to mainstay wrinkle therapy. The hand-held functionality enables the patient to self-administer treatment. The participant satisfaction was assessed through an anonymous survey. The results from the anonymous survey, as seen in figure 4, show that 99% of users felt the NIRA Skincare Laser was easy to use and 87% of users enjoyed using the NIRA Laser. The participants’ high satisfaction ratings suggest that this device is easy to use and could perform successfully in the home market. This study has revealed that low power laser treatment over a number of weeks has the ability to visibly reduce wrinkles. Further studies could be performed in combination with topical treatments and medications to see if wrinkle reduction has greater improvements. References 1. Tan, MD, FRCPC, J. K. L. Tan. "Psychosocial Impact of Acne Vulgaris: Evaluating the Evidence." Skin Therapy Letter 9.7 (2004). Web.06 June 2011. 2. Sugla, Sandeep. "Anti-aging Products and Services: The Global Market." Market Research Reports, Industry Analysis, Newsletters and Conferences. BCC Research, May 2009. Web. 06 June 2011. 3. Goldberg, David J., Arlene S. Rogachefsky, and Sirunya Silapunt. "Non-Ablative Laser Treatment of Facial Rhytides: A Comparison of 1450-Nm Diode Laser Treatment with Dynamic Cooling as Opposed to Treatment with Dynamic Cooling Alone." Lasers in Surgery and Medicine 30.2 (2002): 79-81. 4. Friedman, Paul M., et al. "Treatment of Inflammatory Facial Acne Vulgaris with the 1450-Nm Diode Laser: A Pilot Study." Dermatologic Surgery 30.2 (2004): 147-51. 5. Astner, Susanne, and Tsao, Sandy S. "Clinical Evaluation of a 1,450-Nm Diode Laser as Adjunctive Treatment for Refractory Facial Acne Vulgaris." Dermatologic Surgery 34.8 (2008): 1054-61. 6. Dams, Susanne. “Heat shocks enhance procollagen type I and III expression in fibroblasts in ex vivo human skin.” Skin Research and Technology. 17(2) (2011): 167-180. 7. Dams, Susanne. “The Effect Of Heat Shocks In Skin Rejuvenation.” Technische Universiteit Eindhoven; 2010.
Learn more
Collagen Myths You Should Stop Believing
TL;DR Most "collagen boosters" don't rebuild collagen directly-large collagen molecules in creams sit on the surface, and supplement quality varies. Real results come from signaling your skin to make its own collagen (vitamin C, retinoids, peptides) and from light-based devices; progress is gradual (8-12 weeks). NIRA Pro's FDA-cleared, non-fractional 1450nm laser safely heats the dermis to trigger collagen production with no downtime-2 minutes daily. - Skip myths: creams don't add collagen; supplements differ and aren't tightly regulated.- Do what works: vitamin C/retinoids/peptides + consistent, non-invasive laser use.- Set expectations: early changes ~4 weeks; meaningful remodeling in 2-3+ months. If you’ve ever bought a collagen supplement after seeing before-and-after photos on Instagram, only to feel underwhelmed months later, you’re not alone. Collagen has become one of the buzziest words in beauty, and it shows up everywhere: gummies, powders, creams, sheet masks, and influencer-sponsored miracle routines. But here’s the thing: not all of these “collagen boosters” actually work the way they claim to. Let’s break down the biggest collagen myths and what supports your skin’s natural collagen synthesis—because when you understand what’s real, you can stop wasting time (and money) on what’s not. Myth #1 – Collagen Creams Can Rebuild Collagen in Your Skin It sounds like it should work—apply collagen directly to your skin, and boom: firmer, smoother texture. But it’s not that simple. Here’s the reality: most collagen molecules are too large to penetrate the skin barrier. That means they sit on the surface, doing little beyond hydration. You’re better off using ingredients that help your skin make its own collagen. Ingredients like Vitamin C, peptides, and retinoids signal the skin to produce more collagen on its own—no fake promises, just real biological triggers. Want to know which peptides are worth it? This breakdown of the best peptides for skin tightening explains how they work. Myth #2 – All Collagen Supplements Are Created Equal A collagen powder is a collagen powder, right? Not quite. There are different types: hydrolysed collagen, collagen peptides, and marine collagen, and not all are absorbed or used by the body in the same way. Even among hydrolysed forms, the quality, source, and processing can change how effective they are. Some early studies suggest collagen supplements help improve skin hydration and elasticity, only when paired with other nutrients your body needs to produce collagen, like amino acids and Vitamin C. And keep in mind: supplements aren’t regulated like medications. What’s on the label isn’t always what’s in the jar. Myth #3 – Collagen Loss Only Affects Older Skin It’s easy to assume collagen is only a concern once you hit your 50s. But collagen levels start dropping in your mid-20s. You might not see it right away, but the shift begins early. That means your “future face” is being shaped right now. Starting collagen-supporting habits earlier—like using peptides, antioxidants, or non-invasive treatments—can help maintain skin elasticity before deep lines and sagging settle in. If you’re wondering when this shift begins for most people, this piece on when you start losing collagen lays it out clearly. Myth #4 – You Can’t Restore Collagen After a Certain Age A lot of people believe that once collagen is gone, it’s gone for good. Not true. Your body’s ability to produce collagen slows, but it doesn’t stop. The trick is giving your skin the right signals and support. That includes ingredients like retinoids, Vitamin C, and peptides, yes—but it also includes light-based devices like lasers, which work by triggering your body’s natural wound-healing and skin renewing responses. Those processes include rebuilding collagen in all layers of the skin, including the deeper layers of the skin. With consistency, these methods can improve firmness, texture, and elasticity—even if you haven’t started until your 50s or 60s. Myth #5 – Results from Collagen Treatments Are Instant Collagen doesn’t rebuild overnight. The process of collagen synthesis and skin remodeling takes time—often 8 to 12 weeks to see visible changes. That’s because your skin needs time to regenerate new collagen through a 7-step biochemical process which concludes with robust crosslinking to give the skin a deeply layered structure. If you’ve ever tried a collagen booster for two weeks and gave up, chances are you didn’t give it enough time. Think of it like going to the gym—you won’t see muscle tone after one workout. And just like going to the gym, you will start to see results after about 4 weeks, but this is just the beginning, and continuing for 3-4 months is necessary to see transformational results. The skin transformation follows this same principle. FDA-Cleared Laser Technology Now for the science-backed part of this conversation: collagen laser treatments. The NIRA Pro Laser uses non-fractional laser technology to safely heat the dermis and trigger natural collagen production—without pain, downtime, or surface damage. FDA-cleared Clinically proven to reduce wrinkles in 90 days Painless and non-invasive Safe for all skin types Just two minutes a day This is the same 1450nm laser wavelength trusted by dermatologists, now available in a device built for daily, at-home use. And it works—because it’s not pretending to "add" collagen. It’s stimulating your body to rebuild what it naturally needs to renew skin and revitalize your appearance. Read more about the science behind this approach in our non-fractional laser technology guide. The Bottom Line on Collagen Boosters There’s a lot of noise out there. Not everything that claims to “boost collagen” actually does. But collagen can be supported, at any age, with the right combination of smart ingredients, consistent care, and proven technology. Skip the fads. Stick to what works. And if you're serious about improving skin firmness and reducing wrinkles, the NIRA Pro Laser is a real solution that helps rebuild collagen from the inside out.
Learn more
How to Stimulate Collagen Production Without Injections
TL;DR Collagen declines from your mid-20s, but you can nudge skin to rebuild itself-no needles needed-by stacking smart habits (protein + vitamin C, sleep, SPF), proven topicals (retinoids, peptides, HA), and non-fractional at-home lasers that heat the dermis to stimulate fibroblasts. NIRA Pro (1450 nm) is FDA-cleared and designed for quick, painless daily sessions that gradually smooth fine lines and restore firmness in ~60-90 days. - Daily stack: protein + vitamin C, hydrate/sleep, SPF 30+; use vitamin C (AM), retinol (PM), and HA for plumpness.- Laser boost: treat clean skin first (NIRA Pro), then layer serums; avoid strong acids the same day.- Expectation: improvements build over weeks-consistency beats intensity; track results across face, neck, chest, and hands. You can feel it before you see it. One morning, the skin under your eyes looks a little thinner. A smile photo shows lines that didn’t used to be there. That firm, smooth texture? It’s just not bouncing back like it used to. If you’ve had that moment, you’re not alone, and you don’t have to default to injections. There are smarter, non-invasive ways to support your skin’s natural collagen production—from your face to your neck, chest, and even hands. Collagen naturally breaks down with time. However, with the right combination of daily habits, smart skincare, and at-home technology, you can encourage your skin to rebuild itself, no needles or fillers required. Looking for a face-focused guide? Read our complete collagen restoration blog here. Collagen Does More Than You Think It’s what holds everything together. Collagen gives skin its structure. It keeps things firm, smooth, and lifted. But starting in your mid-20s, production starts slowing down. A little less each year. By your 40s and 50s, that adds up—especially if you’ve had sun exposure, stress, or less sleep than you'd like to admit. Fine lines settle in. Skin starts to feel thinner. That’s not just age. It’s collagen loss in real time. If you’re curious about when this starts and why it feels like it sneaks up on you, this guide on when you start losing collagen breaks it down clearly. The short version? Your skin is constantly working to maintain collagen, but you can give it a significant advantage with the right support. Ways to Support Collagen That Don’t Involve a Needle No syringes, no clinic bills, no downtime. These approaches support collagen production in ways your skin already understands naturally. Food, Sleep, and Small Daily Moves Collagen starts inside—literally. Your body needs the right fuel to make it. Protein gives your body the amino acids it uses to build collagen. Think chicken, fish, eggs, tofu. Vitamin C helps convert those amino acids into usable collagen. Load up on citrus, berries, and bell peppers. Antioxidants (like those in leafy greens and green tea) protect the collagen you already have. Water matters more than you think. Dehydrated skin looks more lined—even if your collagen is fine. Sleep is when your skin does most of its repair work. No magic product will make up for five hours a night. None of this is complicated. But it stacks up. What You Put on Your Skin Can Help Too Skincare won’t rebuild collagen overnight. But used consistently, the right ingredients can support skin renewal and firmness. Retinoids (like retinol) encourage collagen-producing cells to work harder. Peptides are little messengers that tell your skin to repair itself. Vitamin C serums protect against environmental damage and support firmness. Hyaluronic acid doesn’t directly make collagen, but it plumps and hydrates the skin so it looks smoother while you build deeper results. The goal isn’t perfection—it’s consistency. Let your skin respond to a routine that supports it every day. Do Collagen Supplements Work? They might. Some research says hydrolyzed collagen peptides (the kind in powders or capsules) can help skin look more hydrated and elastic over time. But they’re not miracle pills. Think of them as one part of the routine, not the entire plan. At-Home Laser Treatments That Stimulate Collagen Skincare works on the surface. But to really stimulate collagen, you need to reach the dermis—that deeper layer where collagen actually lives. That’s where collagen laser treatment comes in. What a Collagen Laser Actually Does Professional lasers use heat to create tiny “injuries” in the skin, which kicks off your body’s natural healing response. That response? It includes building new collagen. Now, that used to mean going into a clinic. Redness, peeling, downtime. But non-invasive at-home lasers have changed the game. Non-fractional laser technology works by gently heating the dermis without damaging the surface. It’s targeted, safe for daily use, and doesn’t make you look like you’ve been sunburned for three days. Do At-Home Lasers Work for Wrinkles? In short, yes, especially if you’re looking for a non-invasive alternative to Botox or fillers. The NIRA Pro Laser(2nd Gen) is a perfect example. It uses 1450nm non-fractional laser technology—the same wavelength trusted by dermatologists—to gently heat the dermis and activate natural collagen production. No damage to the surface. No pain. No downtime. With 50% more power and 35% faster treatments, it’s our most advanced device yet. Just two minutes a day delivers professional-grade wrinkle reduction, smoothing fine lines and restoring firmness over time. And because it’s FDA-cleared, safe for all skin tones, and app-connected for tracking and insights, it’s never been easier to keep up with a routine that actually works. Best of all, there are no injections involved—just your skin doing the work with the right signal. Supporting Collagen Long-Term Looks Like This You don’t need a 10-step routine. Or a clinic membership. You just need to commit to a few things that work and give them time to show up in your skin. Nourish your skin from the inside. Support it on the surface with proven ingredients. Treat it deeper with at-home tools that help rebuild what’s been lost. And maybe most important: be patient. Collagen doesn’t rebuild in a week. But if you give your skin the right signals, it knows what to do. Frequently Asked Questions How is an at-home laser different from Botox or fillers? Botox freezes movement. Fillers add volume. At-home lasers encourage your own collagen to come back. It’s your skin doing the work—it just needed the nudge. How long does it take to see results? Most people start to see visible changes in 60 to 90 days. Because the collagen cycle takes time, results build gradually. Is it safe for all skin types? Yes, if it’s non-fractional and FDA-cleared. Look for devices tested for safety around sensitive areas like the eyes and lips. Can I use a laser with retinol or vitamin C? Yes—but not at the exact same time. Use your laser on clean skin, and layer serums after. Avoid aggressive acids or peels on the same day you use your device. You can support your skin’s collagen—without the needles. Start with what’s simple. Feed your skin well, stay consistent with ingredients that work, and try a non-invasive at-home laser that helps rebuild collagen naturally. No drastic steps. Just real results, one session at a time.
Learn more
1450 nm vs 1064 nm: Which Laser Wavelength Is Best for Skin Rejuvenation?
TL;DR For non-invasive wrinkle reduction, 1450 nm (water-targeting) lasers concentrate heat in the mid-dermis to stimulate collagen safely across all skin tones; 1064 nm penetrates deeper, interacts more with melanin/hemoglobin, and is better suited to vascular/hair uses than precise dermal remodeling. Evidence cited shows NIRA's 1450 nm device achieves larger Fitzpatrick Wrinkle Score improvements (avg ~1-2 points; up to 3) and stronger real-world outcomes than non-fractional 1064 nm devices, which also carry higher PIH risk. - Why 1450 nm wins: ~300× higher water absorption > focused mid-dermal heating (0.5 mm), collagen remodeling, minimal downtime/safety across Fitz I-VI.- Evidence gap: NIRA (1450 nm) has blinded clinical data and FDA 510(k) support; DermRays (1064 nm) lacks peer-reviewed trials and shows weaker, variable results.- Practical take: For at-home anti-aging, choose 1450 nm (e.g., NIRA) for greater efficacy and comfort; reserve 1064 nm for other indications or pro settings. ABSTRACT This report provides a detailed comparison between the 1450 nm and 1064 nm laser wavelengths for non- invasive skin rejuvenation, emphasizing their use for wrinkle reduction. An analysis of the fundamental physics and tissue interactions of each wavelength is followed by a comparison of real-world applications of two FDA-cleared devices - NIRA and DermRays, that operate at these wavelengths. Introduction Wrinkle reduction remains one of the most sought-after aesthetic treatments as patients seek safe, non-invasive solutions for skin rejuvenation. Skin aging is caused by natural and environment factors. Among the available technologies, diode lasers—particularly NIRA’s 1450 nm laser and DermRays’ 1064 nm laser—have gained prominence for their non-ablative skin-rejuvenation abilities. However, clinical evidence reveals significant differences in their efficacy and potential side effects for wrinkle reduction. NIRA's 1450 nm diode laser are optimized for water absorption and demonstrates superior collagen remodeling capabilities by creating precise thermal stress in the mid-dermis. In contrast, DermRays' 1064 nm diode laser targets deeper tissue treatments and vascular applications based on the wavelength absorption in melanin and hemoglobin. This white paper examines the scientific principles, clinical outcomes, and practical considerations that distinguish these two advanced diode laser systems in wrinkle reduction. By analyzing their tissue interactions, treatment protocols, and real-world performance, this paper provides evidence-based insights to help end users make informed decisions about these technologies for optimal non-ablative skin rejuvenation outcomes. Components of Skin The skin is composed of three distinct layers, each with unique structural and functional properties, depicted in Figure 1.1 The outermost layer, the epidermis, ranges in thickness from 0.03 mm on delicate areas like the eyelids to 2 mm on thicker areas like the palms and sole.2 The average epidermal thickness of the whole face is approximately 0.18 mm.3 The epidermis acts as the body's primary protective barrier and is where melanin, the pigment responsible for skin color and UV protection is found.4 The epidermis has a relatively low water content (15– 20%), making it less responsive to water-targeted laser treatments.4 However, its preservation is critical for avoiding post-treatment complications like scarring or dyspigmentation, especially in darker skin tones. The use of wavelengths with low melanin absorption for the treatment of darker skin tones is preferable to prevent pigmentation issues. Beneath the epidermis lies the dermis, which varies from 0.5 mm to 1.5 mm in thickness and serves as the skin's structural foundation.2 This layer’s thickness averages 0.98 mm in the facial area.3 The dermis is composed primarily of Type I collagen (90% of body’s collagen) for strength, Type III collagen for flexibility, and elastin and hyaluronic acid for elasticity and hydration.5 The dermis is the primary target for collagen- stimulating treatments and also contains hemoglobin, which gives blood its red color and contributes to the skin tone variations in vascular conditions.4 The facial dermis has a 72% water content making it highly responsive to 1450 nm diode lasers, which are absorbed 0.5 mm deep to deliver precise thermal energy to the mid-dermis.4,6 This stimulates fibroblasts to produce new collagen and elastin, leading to wrinkle reduction and skin tightening without damaging the epidermis. Figure 1. Layers of the Skin (Hxtran, 2023) The deepest layer, the hypodermis, consists of fat and connective tissue and ranges dramatically in thickness (0.5 mm to 30 mm) depending on body location and individual adiposity.2 With a water content of just 6– 36%, this layer provides structural support, insulation, and volume, but is not a direct target for non-ablative laser treatments.4 The 1064 nm laser wavelength has low water absorption and penetrates deeper than the epidermis and dermis, around 4 mm deep.7,8 This results in the energy absorbing into the hypodermis and deeper muscle layers. Mechanism of Facial Aging Facial aging is a complex biological process driven by both intrinsic factors, such as genetics and hormonal changes, and extrinsic factors, including UV exposure, pollution, and lifestyle habits like smoking or poor nutrition. Over time, these factors lead to cumulative damage, particularly in the dermis, where critical structural components like collagen, elastin, and hyaluronic acid degrade. This breakdown results in the loss of skin volume/thickness, elasticity, firmness, and hydration, manifesting as fine lines, deep wrinkles, uneven skin tone, enlarged pores, and sagging skin. The Role of Collagen in Aging Collagen, the most abundant structural protein in the skin, is essential for maintaining its strength, elasticity, and volume. Collagen is produced by cells called fibroblasts that are predominantly found in the dermis. Over time, natural aging leads to a 1–1.5% annual decline in collagen production beginning as early as the mid-20s.9 This process is heightened by extrinsic aging factors, including sun exposure, pollution, and unhealthy habits like smoking, that further degrade collagen and elastin. As collagen levels diminish, the skin loses its ability to repair itself, leading to visible signs of aging. Many anti-aging treatments target the dermis to stimulate fibroblasts to increase collagen production, including 1450 nm laser treatment. Absorption Properties Laser-tissue interaction is largely determined by the absorption properties of skin molecules—primarily water, melanin, and hemoglobin. These absorption characteristics determine the depth of penetration, treatment efficacy, and safety profile of different laser wavelengths. See Figure 2 for details.10 1450 nm Absorption The 1450 nm diode laser achieves highly controlled dermal remodeling by using water as its primary chromophore. This wavelength exhibits approximately 300 times greater water absorption than 1064 nm (Fig. 3), allowing it to confine energy precisely within the mid-dermis (0.5 mm depth)—the optimal zone for collagen production stimulation.11 By targeting water, the laser induces controlled thermal stress, which promotes fibroblast activation and collagen remodeling while minimizing damage to the epidermis. Figure 2. Water, Melanin, and Hemoglobin Absorption Spectrum (Wu & Yang, n.d.) In addition, 1450 nm has very low absorption in melanin and hemoglobin which results in absorption almost entirely by water alone. As a result, it is especially effective and comfortable for treating wrinkles, fine lines and superficial lines within the dermis and epidermis without concern for the impacts of melanin (skin color), tattoo effects, or hemoglobin impacts. By focusing energy on the water-rich dermis, devices like the 1450 nm laser maximize collagen remodeling while minimizing risks to surrounding tissues, making them ideal for safe, effective wrinkle reduction. Figure 3. Water Absorption Spectrum (Small, 2025) 1064 nm Absorption In contrast, the 1064 nm wavelength has low water absorption but greater absorption by melanin (~4x more) and hemoglobin (~10x more) than 1450 nm (Fig. 3). Due to its stronger absorption, 1064 nm carries a greater risk of pigmentation issues. Additionally, it penetrates around 4 mm and deeper into the skin, which penetrates beyond the dermis to directly stimulate collagen synthesis (Fig. 4).12 However, absorption in melanin and hemoglobin can result in incidental heating of the dermis, making it a less efficient mechanism than the 1450 nm laser’s mechanism. The deeper penetration makes the 1064 nm wavelength optimal for treating vascular lesions, hair removal, and tattoo removal, but not wrinkle reduction. Laser Mechanisms of Action Non-Fractional 1450nm Lasers NIRA’s 1450 nm diode laser system implements Precision Protein Promotion (P3) technology.13 This innovative approach optimizes thermal stimulation for collagen production while minimizing discomfort and downtime. P3 works by rapidly heating the dermis to above 39°C—the threshold for heat shock protein (HSP) activation—while carefully staying below the pain threshold (~45°C). The system adjusts fluence in real-time, reducing power as skin approaches 45°C to maintain a therapeutic levels at a comfortable temperature range. Unlike fractional lasers that create many small dots of localized damaged zones, P3 technology uniformly heats the dermis for 2 to 5 seconds, ensuring widespread thermal stimulation without damaging the cellular structures. After the laser pulse, the dermis remains above 39°C for approximately 3 seconds which generates HSP production that stimulate the collagen synthesis and overall skin renewing processes. HPSs act as molecular chaperones, promoting new collagen formation (Types I/III) and remodeling of existing collagen.14 The dermal heating below the pain threshold ensures no cellular damage and little to no risk of post-treatment inflammation and redness. The Candela Smoothbeam laser is a clinical-grade non-fractional laser at 1450 nm that operates at a significantly higher fluence than NIRA, driving dermal temperatures well above the pain threshold of 45C°. This clinical laser is intended for 4-6 monthly treatments at higher energy levels and uses a cryogen cooling system to reduce damage to the epidermis. This laser works by the same mechanism of NIRA’s for skin renewing but has significant side effects, including pain, edema, erythema, and hyperpigmentation. Non-Fractional 1064nm Lasers DermRays uses a 1064 nm non-ablative non-fractional laser with an integrated thermoelectric cooling (TEC) system. The TEC pulls heat away from the surface, which DermRays says keeps the skin-contact temperature under 66C° to prevent pain. Most of the laser power absorbs 4 mm or deeper reaching the hypodermis—a layer of fat and connective tissue—or even muscle layers beneath it. This is the same mechanism used in the clinical non-fractional 1064 nm laser from Genesis and Lyra. Figure 4. 1450 nm vs. 1064 nm Skin Penetration (Adapted from "3D medical animation skin layers", 2020) Fractional 1064 nm lasers The fractional 1064 nm devices including DEKA Again and Clarity LPY (Table 1) employ a fractional photothermolysis mechanism. Unlike traditional non-fractional lasers that treat the entire surface, these devices create small columns of thermal damage extending through the entire dermis while sparing surrounding tissue. This triggers a robust wound healing response, stimulating neocollagenesis and elastin remodeling. While the untreated 'bridges' between columns accelerate healing compared to fully ablative treatments, fractional 1064 nm lasers still require significant downtime making them too aggressive for safe home use. Efficacy of Home-use Laser Devices DermRays (1064 nm) While DermRays Revive is FDA-cleared under 510(k) K231910 for wrinkle reduction, hair removal, and skin rejuvenation, it has not been supported by peer-reviewed clinical trials or published histologic evaluations.15 DermRays has conducted a third-party Société Générale de Surveillance (SGS) consumer study involving 28 participants (ages 33–59) over 56 days.16 The results claim a 26.4% reduction in wrinkle count, 25.8% decrease in wrinkle size, and a 6% reduction in wrinkle depth as stated by DermRays website, however, the actual SGS report is not publicly available for confirmation. There was no formal measurement of wrinkle reduction according to the Fitzpatrick Wrinkle Scale (FWS), a tool used to assess the severity of wrinkles, that allows for comparison to other devices. These SGS findings were derived from self-assessment and non-peer-reviewed reports. This type of study has a large confirmation-bias and is not considered scientifically-accurate or a reliable result. There is no publicly available evidence of randomized controlled trials, dermatologist-blinded assessments, or histologic confirmation of collagen remodeling for DermRays. Its clinical efficacy for wrinkle reduction remains unclear in the absence of robust, peer-reviewed evidence. NIRA (1450 nm) In contrast, devices operating at 1450 nm, such as NIRA (K163137, K222685), are supported by FDA-reviewed technical data and a blinded independent clinical study overseen by three medical experts, which demonstrated significant improvement in fine lines and wrinkles and indicated collagen renewal when used consecutively for 90 days.17,18 NIRA’s 1450 nm diode laser system is supported by robust clinical and regulatory evidence. According to its FDA 510(k) submission (K163137), a 76-subject clinical study demonstrated significant improvements in periorbital wrinkles. Notably, 69% of participants showed at least a 1-point improvement on the 9-point Fitzpatrick Wrinkle Score (FWS), with an average of a 2-point improvement, and a maximum improvement of 3 points. Additionally, 68% maintained these improvements 3 months after stopping treatment. 99% of clinical subjects reported the device as easy to use, 95% saw results within 3 months, and 90% recommended the device. Efficacy of Clinical Devices 1450 nm Non-fractional Devices In a clinical trial using the 1450 nm Smoothbeam Laser, FWS scores showed sustained reductions. Improvements began with a 1.05-point decrease at 1 month, rising to 1.3 points by 3 months and peaking at 1.55 points by 6 months (Table 1).19 At the 12-month follow-up, a slight regression to 1.42 points was observed. Side effects included erythema and hyperpigmentation, which was resolved with topical bleaching agents. It is understood that the hyperpigmentation was due to the dynamic cooling used during the treatments rather than the wavelength or fluence delivered, since 1450 nm is not well absorbed by melanin. The treatment was well tolerated, with mild to moderate discomfort. A separate trial using the same device reported more dramatic results, with a 3-point reduction achieved by the 6-month endpoint (Table 1).20 Treatment was tolerated by all patients, with slight discomfort, but no adverse effects were reported. 1064 nm Non-fractional Devices A study evaluating Cutera’s Laser Genesis demonstrated an average wrinkle improvement of 0.8 points on the after 3 months, with no adverse effects (Table 1).21 Another trial using the Laserscope Lyra reported a 0.48-point reduction at 3 months, which increased to 1.5 points after 5 months (Table 1).22 Side effects in this study included moderate pain, mild edema, and erythema. These non-fractional 1064nm laser results are most likely to be the best for comparison to the DermRays non-fractional results. It is unlikely for the DermRays efficacy to be greater than the results of these clinical results, especially considering the much lower fluence of DermRays compared to clinical devices Figure 5. NIRA's Precision (Left) and Pro (Right) Home-use Devices 1550 nm Fractional Devices 1550 nm fractional laser devices are widely used in dermatology offices for wrinkle reduction and facial rejuvenation, as well as for treating the neck and other cosmetic areas. The 1550 nm wavelength has a water absorption rate similar to that of 1450 nm as shown in Figure 2, but it penetrates slightly deeper into the dermis. This deeper penetration allows the fractional laser to target and thermally disrupt full columns of tissue through the dermis within each fractional treatment spot. The controlled damage stimulates the body’s natural healing process, where the unaffected surrounding tissue aids in repairing, promoting the production of new collagen and dermal remodeling. Over a series of treatments—typically three or more—the fractional zones are randomized, ensuring comprehensive dermal renewal. With each session, the skin undergoes gradual improvement, resulting in smoother, rejuvenated texture and tone. Clinical studies showed that fractional laser treatments slightly improved FWS scores compared to 1450 nm non-fractional devices. However, common side effects of the 1550 nm fractional lasers included transient and prolonged erythema and moderate pain scores. The FRAX1550 laser achieved a 2.4-point reduction in FWS, while the Fraxel Xena device demonstrated a 0.7-point reduction at 1 month and a 2.91-point reduction at 3 months.23, 24 These results are comparable to the NIRA home device at a 2-point average reduction, that had no serious adverse effects. 1064 nm Fractional Devices A clinical study evaluating the Clarity LPYTM laser demonstrated progressive wrinkle reduction over time, with FWS improvements of 0.58 points at 1 month, 1.52 at 2 months, and 2.11 at 3 months.25 Patients reported mild pain and transient erythema as common side effects. Comparatively, the DEKA Again device (Fig. 6) achieved a 1.6-point FWS reduction, while the Discovery Pico Plus showed a 1.82-point reduction, with similar reports of mild discomfort and erythema.26,27,28 These fractional lasers work by delivering focused energy to thermally disrupt targeted tissue, triggering a controlled wound-healing response that promotes collagen remodeling and dermal regeneration. While this approach yields greater wrinkle reduction than non- fractional treatments, it also carries a higher risk of side effects whether it uses an ablative or non-ablative approach. It is important to consider that the mechanism of action differs significantly from non-fractional 1064 nm devices. Since fractional lasers induce focused thermal injury zones and rely on fractional photothermolysis, their results cannot be directly compared to those of non- fractional systems like DermRays’ device. Thus, it is best to compare the DermRays non-fractional performance to that of the clinical 1064nm non- fractional performance. Safety and Pain Considerations T he 1450 nm wavelength, by primarily targeting water, is safe across Fitzpatrick skin types (I–VI) with minimal to no adverse effects. The Fitzpatrick scale is a numerical classification schema for human skin color, with higher numbers indicating darker skin tones. Figure 6. DEKA Again Clinical Device (Again Pro, n.d.) NIRA reaches therapeutic temperatures in a controlled manner to minimize discomfort, providing five energy level options so users can select the level where they feel warmth without discomfort or any side effects. NIRA’s clinical studies found that treating at this level of warmth without side effects yields best-in-class wrinkle reduction. With the clinical results stated below, it is clear that NIRA is a safe and effective treatment for all skin types without adverse effects, unlike other clinical and home-use devices. Because melanin absorbs approximately four times more energy at 1064 nm than 1450 nm, they carry a higher risk of side effects, including erythema, post- inflammatory hyperpigmentation (especially in darker skin tones of Fitzpatrick IV–VI), and often require cooling mechanisms or reduced fluence to improve tolerability and safety. This concentration of power in such dark spots can cause wounds and scarring in the skin. Optimal Wavelength for Anti-aging at Home When comparing in-office clinical lasers and home-use devices, 1064 nm wavelengths demonstrate less pronounced anti-aging effects in the dermis compared to longer wavelengths like 1450 nm and 1550 nm. This is especially true for the non-fractional treatment devices. The difference stems from 1064 nm’s low water absorption, which results in the laser energy to passing through the dermis with little absorption (and related efficacy). Most 1064 nm laser power penetrates to approximately 4 mm and deeper—reaching the hypodermis and muscle layers rather than being concentrated in the dermis. In clinical studies, non-fractional 1064 nm devices showed relatively low wrinkle reduction, with FWS reductions ranging from 0.48 to 1.0 points. This wavelength also carries a higher risk of side effects, particularly in darker skin tones (Fitzpatrick IV-VI), where melanin absorption can lead to post-inflammatory hyperpigmentation or thermal injury. In contrast, 1450 nm and 1550 nm lasers—with their higher water absorption—deliver more energy to the dermis, promoting collagen remodeling with fewer risks for pigmentation complications. The 1450 nm non-fractional device had comparable results to the clinical fractional 1064 nm and 1550 nm lasers (despite the different mechanism of action for the fractional approach). These improved results were regardless of the fact that the 1064 nm lasers used significantly higher fluence (J/cm2), demonstrating that targeting of the dermis with a precise wavelength is much more important than the overall fluence and power of the laser. NIRA achieved an average of 1.4- and 2-point reductions in FWS after 3 and 7 months with a 3-point maximum reduction by the end of the treatment cycle. This outperformed the highest reduction for a non- fractional clinical-grade 1064 nm laser which scored an average reduction of 0.48 after 3 months and 1.0 after 6 months. Thus, NIRA provided 2 to 3 times the wrinkle reduction as compared to non-fractional 1064nm lasers. NIRA was also comparable to the greatest reduction for a fractional 1064 nm laser which was 2.11. This is significant because non-fractional 1064 nm lasers typically require higher energy to penetrate deeply, increasing the risk of hyperpigmentation in darker skins tones, while delivering smaller cosmetic improvements. Fractional 1064 nm lasers, though effective, often involve more downtime and side effects due to their ablative or thermal disruption mechanisms. NIRA’s performance demonstrates efficacy rivaling fractional lasers with a safer, gentler profile. This makes NIRA’s 1450 nm lasers promising options for patients seeking visible anti-aging results with minimal downtime. Efficiency through Energy Delivery A 17-week comparative simulation was conducted for the NIRA and DermRays user guidelines, assuming a user adheres to 80 pulses per day. Under these conditions, NIRA—designed for daily use—delivered approximately 65,688 J of total energy, while DermRays, following a tapering protocol, delivered only 32,384 J (Fig. 7). This demonstrates that NIRA provides about two times more cumulative energy exposure over the treatment period. Consistent and sufficient energy delivery is critical for effective collagen remodeling and wrinkle reduction. Higher total energy exposure ensures more sustained stimulation of fibroblasts, promoting better structural repair in the dermis. NIRA’s greater energy delivery— combined with its 300 times greater water absorption— likely explains its superior anti-aging outcomes. These factors enable more robust neocollagenesis, leading to visibly improved skin texture and firmness over time. Thus, under the specified protocols, NIRA’s sustained high-energy delivery and superior dermal absorption are key drivers of its enhanced anti-aging performance compared to DermRays. Conclusion In conclusion, the 1450 nm wavelength is biomechanically superior for wrinkle reduction due to its high-water absorption, selective dermal targeting, and fewer side effects. Devices like NIRA maximize this advantage by delivering consistent, controlled energy daily into the mid-dermis, where collagen production is most effectively stimulated. The wavelength’s low melanin absorption also ensures safe and uniform results across all Fitzpatrick skin types, minimizing the risk of hyperpigmentation or overheating. While 1064 nm lasers like DermRays are effective for deeper tissue penetration and broader applications such as vascular lesions and pigmentation, they are less efficient for precise collagen remodeling and carry greater risk of discomfort and pigmentation issues in darker skin tones due to higher melanin absorption. Additionally, their treatment schedules are less frequent and deliver less cumulative energy over time. Overall, for regular home-use devices, the 1450 nm non- fractional approach (e.g. NIRA) delivers 2 to 3 times the anti-aging efficacy with significantly lower side-effects as demonstrated by multiple clinical papers reviewed. Figure 7. DermRays vs. NIRA Energy Comparison over 17 Weeks Table 1. Clinical Results Summary Wrinkle scale scores above are normalized to Fitzpatrick 9-point scale. Link To: Common Misconceptions and Considerations References Hxtran. (2023, April 22). File:Different layers of skin.png - Wikimedia Commons. https://commons.wikimedia.org/wiki/File:Different_layers_of_skin.png#Licensing The skin. (n.d.). Oncobeta. https://www.oncobeta.com/your-health/nmsc-info/the-skin Meng, Y., Feng, L., Shan, J., Yuan, Z., & Jin, L. (2022). Application of high-frequency ultrasound to assess facial skin thickness in association with gender, age, and BMI in healthy adults. BMC Medical Imaging, 22(1). https://doi.org/10.1186/s12880-022-00839-w Setchfield, K., Gorman, A., Simpson, A., Somekh, M., & Wright, A. (2023). Relevance and utility of the in-vivo and ex-vivo optical properties of the skin reported in the literature: A review [Invited]. Biomedical Optics Express, 14(7), 3555–3583. http://dx.doi.org/10.1364/BOE.493588 Professional, C. C. M. (2025, June 6). Collagen. Cleveland Clinic. https://my.clevelandclinic.org/health/articles/23089-collagen Laubach, H., Astner, S., Watanabe, K., Clifford, J., Rius‐Diaz, F., Zurakowski, D., & Manstein, D. (2009). Effects of a 1,450 nm diode laser on facial sebum excretion. Lasers in Surgery and Medicine, 41(2), 110–115. https://doi.org/10.1002/lsm.20672 Meesters, A. A., Pitassi, L. H. U., Campos, V., Wolkerstorfer, A., & Dierickx, C. C. (2013). Transcutaneous laser treatment of leg veins. Lasers in Medical Science, 29(2), 481–492. https://doi.org/10.1007/s10103-013-1483-2 Kaub, L., & Schmitz, C. (2023b). Comparison of the Penetration Depth of 905 nm and 1064 nm Laser Light in Surface Layers of Biological Tissue Ex Vivo. Biomedicines, 11(5), 1355. https://doi.org/10.3390/biomedicines11051355 Reilly, D. M., & Lozano, J. (2021). Skin collagen through the lifestages: importance for skin health and beauty. Plastic and Aesthetic Research, 8, 2. https://doi.org/10.20517/2347-9264.2020.153 Wu, O., & Yang, K. (n.d.). 1470 nm diode lasers enable home skin rejuvenation. https://digital.laserfocusworld.com/laserfocusworld/202104/MobilePagedArticle.action?articleId=1676230#articleId1676230 Small, R. (2025, April 22). Wrinkle Reduction with Nonablative Lasers. Clinical Gate. https://clinicalgate.com/wrinkle-reduction-with-nonablative-lasers/ Note. Adapted from “File:3D medical animation skin layers.jpg”. (2020, January 15). Wikimedia Commons. https://commons.wikimedia.org/wiki/File:3D_medical_animation_skin_layers.jpg Bean, D., Huang, Z., Feldchtein, F., Govoni, K., & Dermal Photonics Corp. (NIRA Brand). (2019, January 20). Non-fractional dynamic treatment of wrinkles with low power, single-pass 1450nm handheld laser. Dams, S. D., De Liefde‐van Beest, M., Nuijs, A. M., Oomens, C. W. J., & Baaijens, F. P. T. (2011). Heat shocks enhance procollagen type I and III expression in fibroblasts in ex vivo human skin. Skin Research and Technology, 17(2), 167–180. https://doi.org/10.1111/j.1600-0846.2010.00473.x Tanisha Hithe. (n.d.). Letter to Wuhan Lotuxs Technology Co., Ltd. regarding 510(k) Premarket Notification for DermRays Revive. https://www.accessdata.fda.gov/cdrh_docs/pdf23/K231910.pdf DermRays revive Skincare Laser for Anti-Aging, Glow like Never before. (n.d.). DermRays. https://www.dermrays.com/products/dermrays-revive Ashar, B. S. (Director). (2017). Letter to Dermal Photonics Corporation regarding Nira Beauty Skin Laser 510(k) Premarket Notification. In Food and Drug Administration. https://www.accessdata.fda.gov/cdrh_docs/pdf16/K163137.pdf Wang, J., Dermal Photonics Corp, & Feldchtein, F. (2023). Letter to Dermal Photonics Corp regarding 510(k) Premarket Notification for NIRA Model 2. In U.S. Food & Drug Administration, U.S. Food & Drug Administration. https://www.accessdata.fda.gov/cdrh_docs/pdf22/K222685.pdf Tanzi, E. L., Williams, C. M., & Alster, T. S. (2003). Treatment of facial rhytides with a nonablative 1,450-Nm diode laser: a controlled clinical and histologic study. Dermatologic Surgery, 29(2), 124–128. https://doi.org/10.1046/j.1524-4725.2003.29046.x Trelles, M. A., Allones, I., Levy, J. L., Calderhead, R. G., & Moreno-Arias, G. A. (2004). Combined Nonablative Skin Rejuvenation with the 595- and 1450-nm Lasers. Dermatologic Surgery, 30(10), 1292–1298. https://doi.org/10.1111/j.1524-4725.2004.30405.x Tanaka, Y., Matsuo, K., & Yuzuriha, S. (2011). Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians. Clinical Cosmetic and Investigational Dermatology, 123. https://doi.org/10.2147/ccid.s22841 Lee, M. C. (2003). Combination 532-Nm and 1064-Nm lasers for noninvasive skin rejuvenation and toning. Archives of Dermatology, 139(10), 1265. https://doi.org/10.1001/archderm.139.10.1265 Tidwell, W. J., Green, C., Jensen, D., & Ross, E. V. (2018). Clinical evaluation and in-vivo analysis of the performance of a fractional infrared 1550 nm laser system for skin rejuvenation. Journal of Cosmetic and Laser Therapy, 20(6), 360–363. https://doi.org/10.1080/14764172.2018.1511915 Moon, H., Yun, W., Lee, Y. J., Lee, M., & Chang, S. (2015). A prospective, randomized, double-blind comparison of an ablative fractional 2940-nm erbium-doped yttrium aluminum garnet laser with a nonablative fractional 1550-nm erbium-doped glass laser for the treatment of photoaged Asian skin. Journal of Dermatological Treatment, 26(6), 551–557. https://doi.org/10.3109/09546634.2014.999020 Hong, J. S., Park, S. Y., Seo, K. K., Goo, B. L., Hwang, E. J., Park, G. Y., & Eun, H. C. (2014). Long pulsed 1064 nm Nd:YAG laser treatment for wrinkle reduction and skin laxity: evaluation of new parameters. International Journal of Dermatology, 54(9). https://doi.org/10.1111/ijd.12626 High tech medical. (n.d.). https://www.hightechmedical.com.au/product/again-pro Piccolo, D., Crisman, G., Gallo, G., Fusco, I., & Conforti, C. (2023). Long Pulsed 1064 nm Nd:YAG Laser Treatment for Skin Laxity and Wrinkle Reduction: Evaluation of New Handpiece and “in Motion” Setting Technique—A Case Series Study. Photobiomodulation Photomedicine and Laser Surgery, 41(6), 297–299. https://doi.org/10.1089/photob.2023.0024 Van Thanh Le, T., Nguyen, P. T., Le, V. A., Ta, Q. H., Zevini, A., Martinelli, D., & Barini, R. (2025). Fractional 1064 nm Nd:YAG picosecond laser for Asian skin rejuvenation: clinical efficacy and the role of photoprotective behaviours. Lasers in Medical Science, 40(1). https://doi.org/10.1007/s10103-025-04453-4 Rahman, Z., & Ostrowski, R. (n.d.). A clinical and photographic evaluation of an at-home 1440 nm skin rejuvenating laser. [Unpublished manuscript]. Stanford University; Tria Beauty, Inc.
Learn more
How to Fix Hooded Eyes Naturally at Home
TL;DR Hooded eyes are often driven by collagen loss and habits (rubbing, sleep position, UV), but steady at-home care can lift and firm the area over time. Pair gentle daily habits (massage, peptides/HA eye creams, SPF) with a non-fractional at-home laser-e.g., the FDA-cleared NIRA Precision-for collagen stimulation and visible tightening in ~60-90 days. - Routine: cleanse > light massage > peptide/HA eye cream > daily SPF; maintain good posture/sleep on back.- Device boost: use NIRA Precision daily around eyes (no tugging) to stimulate collagen without downtime.- Avoid: rubbing/pulling lids, unregulated tools, skipping hydration/SPF; seek a pro if no change after 3-6 months or vision is affected. How to Fix Hooded Eyes Naturally at Home As skin naturally changes with time, the eye area is often one of the first places to show it. That soft fold above the lash line might start to dip lower, giving eyes a more “hooded” appearance. But here’s the encouraging part: while this shift is common, it’s also something you can absolutely work with. With the right care, consistency, and some thoughtful at-home strategies, it is possible to support firmer, smoother skin around the eyes, without turning to surgery or downtime. Let’s talk about why hooded eyes happen, what actually helps, and how small daily choices can make a noticeable difference over time. Why Hooded Eyes Happen Hooded eyes aren’t just genetic, they can also become more pronounced with age and environmental exposure. The skin around the eyes is thinner than anywhere else on the face, making it one of the first areas to show signs of change. Aging and Collagen Loss As we get older, our natural collagen and elastin levels begin to decline. Collagen is what keeps skin firm and structured, while elastin allows it to bounce back. Around the eye area, this results in sagging upper lids, fine lines, and puffiness. Without that underlying support, the upper eyelid starts to fold over itself, creating the “hooded” appearance that can make eyes look smaller or more tired. If you’re curious about how collagen supports skin integrity, this blog on how to restore collagen naturally offers a more helpful background. Lifestyle and Environmental Factors Daily habits can speed up changes around the eyes: Rubbing your eyes can break down delicate tissue and stretch the skin Sleeping face-down or on your side may cause fluid buildup and creasing UV exposure and blue light contribute to faster collagen degradation Poor hydration or a diet low in antioxidants can dull skin’s natural repair mechanisms These might seem small, but over months or years, they add up. To protect your skin overall, here are seven effective ways to prevent premature aging that complement your eye care routine. Daily Habits That Support a Natural Eye Lift If you want to support your eyelid skin naturally, start with your daily routine. These subtle changes won’t dramatically lift skin overnight, but over time, they support firmness, circulation, and collagen production. Gentle Cleansing and Eye Massage Start and end your day with a gentle cleanser. Avoid rubbing or pulling the skin around the eyes; instead, gently pat the product in. Incorporating a soft massage with your ring finger (the weakest finger, so least likely to tug) can help stimulate blood flow and support lymphatic drainage, reducing puffiness and tension. Try this simple massage technique: Tap under the eyes in a semi-circle motion from the inner to outer corner Gently press under the brow bone, lifting slightly upward as you move along Repeat morning and night for 30 seconds Eye Creams with Firming Ingredients Certain ingredients can help smooth and tighten the appearance of skin: Peptides support collagen production and skin structure Hyaluronic acid plumps skin and draws in hydration Caffeine can help reduce swelling and firm up the area temporarily Look for lightweight, fragrance-free formulas designed specifically for the eye area. Apply gently with a tapping motion to avoid stretching the skin. Facial Exercises and Posture Awareness Face yoga or targeted eye exercises can help tone the muscles around the eye socket. Some people find these helpful in maintaining lift and reducing tension. You can also try: Holding a squint for 10 seconds (without wrinkling your forehead) Raising your brows while keeping your eyelids closed Practicing neck and shoulder alignment to reduce eyebrow strain Poor posture, especially forward head tilt, can affect how the skin around the eyes appears by increasing pressure on facial muscles and contributing to drooping brows. At-Home Devices That Can Help Tighten Eyelid Skin Technology can complement your daily routine and give your skin a boost, especially when it comes to collagen stimulation. Why Laser-Based Devices Work Laser-based devices, including non-fractional lasers, have been shown to help stimulate collagen in the skin by gently heating the deeper layers (dermis) without damaging the surface. This process triggers your body’s natural repair response, encouraging new collagen growth. Unlike LED, lasers offer more concentrated stimulation and longer-lasting results. If crow’s feet are also a concern, laser treatments can help target those fine lines too — learn more about how lasers work for crow’s feet. The result? Skin gradually becomes firmer, smoother, and more resilient, making these tools especially effective for thin, delicate skin like the upper eyelids. Unlike LED, lasers offer more concentrated stimulation and longer-lasting results. If you're interested in how this technology works, you can read more about the science behind NIRA. The NIRA Precision Laser for Hooded Eyes Designed specifically for use around the eye area, the NIRA Precision Laser is FDA-cleared and clinically proven to target fine lines and wrinkles. Key benefits: Non-invasive and painless Safe for daily use Targets collagen production without damaging the skin barrier Compact and easy to integrate into your routine Many users report seeing visible improvement in upper eyelid lift and tightness after 60–90 days of consistent use. What to Avoid When Treating Hooded Eyes at Home In an effort to “fix” hooded eyes quickly, some common mistakes can actually make the issue worse: Tugging or pulling the skin: Stretching thin eyelid skin causes more sagging over time Using tools not meant for the eye area: Unregulated devices can be unsafe or ineffective Skipping SPF: UV damage is one of the biggest accelerators of skin thinning Dehydration and inconsistent routines: Hydrated skin responds better to any treatment, natural or tech-based When to Consider Professional Guidance While at-home methods can offer meaningful improvement over time, there are limits to what skincare and tools can do. Consider consulting a dermatologist or oculoplastic specialist if: Your vision is being affected by excess lid skin You’ve seen no change despite 3–6 months of consistent care You want to explore surgical options like blepharoplasty For those who want more noticeable or immediate results, professional procedures can lift and remove excess skin with long-term outcomes, but they also come with hefty costs, downtime, and risks. See Results Without Surgery Fixing hooded eyes naturally is about small, smart steps that support your skin long term. If you're ready to support firmer, smoother skin around your eyes—without surgery—the NIRA Precision Laser is FDA-cleared for exactly that. See before-and-after results from real users and try it risk-free.
Learn more
What Age Does Collagen Loss Begin and How It Affects Your Skin
TL;DR Collagen production starts declining in your mid-to-late 20s (~1%/yr after 30), accelerating with UV, stress, poor sleep, and sugar-showing up as fine lines, thinner skin, and less "bounce." Support it early and consistently with daily SPF, vitamin C, retinol/peptides, hydration, and smart devices; NIRA's FDA-cleared, painless at-home laser stimulates dermal collagen and can deliver visible results in ~10-12 weeks. Action step: pair NIRA use with SPF every morning and vitamin C a.m./retinol p.m. for a simple, preventive collagen routine. Collagen isn’t just a buzzword in skincare - it’s the foundation of firm, youthful-looking skin. But at what age does collagen loss actually begin, and how does it show up on your face? Let’s break down when the decline starts, what it means for your skin’s appearance, and how you can stay ahead of it. Why Collagen Matters for Skin Health Collagen is the unsung hero of youthful, glowing skin. It’s a structural protein that acts like scaffolding for your skin, keeping it firm, elastic, and resilient. Think of it as the “glue” that holds everything together. As we age, our collagen levels naturally start to drop. This decline is tied closely to collagen levels by age, and the change becomes more noticeable in our 30s and 40s. For women, especially, hormonal shifts during perimenopause and menopause accelerate the collagen loss with age, making skin thinner, drier, and more prone to fine lines and sagging. Simply put, collagen is essential for skin that looks and feels healthy. The earlier we understand this, the better equipped we are to care for our skin long term. When Do You Start Losing Collagen? So, when do you start losing collagen? According to dermatologists and scientific studies, collagen production starts to slow down in your mid-to-late 20s. Yikes, right? By the time you hit 30, your body produces about 1% less collagen every year. And it's not just age working against us. Collagen loss speeds up due to: UV exposure (hello, unprotected sunbathing) Smoking High sugar diets Chronic stress Lack of sleep Each factor contributes to slowing collagen production, meaning your skin’s ability to bounce back takes a serious hit. The Visible Signs of Collagen Loss Here’s the thing—collagen doesn’t just disappear overnight. It’s a gradual decline, but the signs of collagen loss in the face become unmistakable: Fine lines around the eyes and mouth Skin that feels thinner or less plump Reduced elasticity (that “bounce back” feel) Dullness and uneven tone More visible pores and slower healing These early warning signs usually begin showing in your 30s, but for some, even earlier. The key is catching them early and taking action before the damage becomes harder to reverse. Supporting Collagen Naturally from an Early Age Good news: you don’t need to wait for your skin to show signs of aging to start supporting collagen. Prevention is where the magic happens. Here’s how to increase collagen naturally: Lifestyle Habits SPF every day: The #1 way to prevent collagen breakdown Eat collagen-friendly foods: Think berries, bone broth, leafy greens, and citrus Stay hydrated: Skin cells are like little sponges—they need water to function Sleep well: Your skin regenerates while you snooze Manage stress: Chronic cortisol is a collagen killer Smart Ingredients Vitamin C: Essential for collagen synthesis Retinol: Boosts cell turnover and stimulates collagen Peptides: Send signals to build more collagen Hyaluronic Acid: Doesn’t build collagen, but helps keep it cushioned and hydrated All of these are your allies in slowing the natural collagen decline. Collagen Treatments You Can Do at Home We get it—life’s busy and spa visits aren’t always on the agenda. That’s where at-home solutions come in. A new generation of tech is leading the way when it comes to collagen treatment for the face at home. Home-Based Collagen-Boosting Tools LED light therapy Microcurrent devices Facial massage tools Laser treatments—like NIRA Let’s talk NIRA. This FDA-cleared, non-fractional laser sends gentle heat into the dermis (the collagen layer of the skin), triggering your body to naturally rebuild collagen. It’s the only painless at-home laser designed by professional laser engineers and dermatologists, offering results comparable to in-office treatments, minus the cost and downtime. Why NIRA Stands Out: Painless and safe to use around the eyes Delivers results in 10–12 weeks with twice-daily use 200x more powerful than LED treatments Stimulates natural collagen without damaging the skin surface Want to explore more? Check out NIRA’s full-feature laser for collagen production. When to Start a Preventive Skincare Routine Wondering when you should start getting serious about collagen? Here’s the breakdown: In Your 20s: Start using sunscreen Add antioxidants like vitamin C Begin introducing gentle treatments like NIRA to stay ahead In Your 30s: Add retinol and peptides Focus on deep hydration Commit to a consistent skincare regimen with proven tools In Your 40s and Beyond: Combine treatments: diet, topicals, and devices like NIRA Hydrate inside and out Address both intrinsic and extrinsic aging The golden rule? Consistency beats intensity. Long-term skin health is about maintaining, not playing catch-up. Final Thoughts Collagen loss starts earlier than most people realize, but that doesn’t mean it’s out of your hands. By understanding the timeline of collagen loss with age, spotting the signs early, and committing to prevention, you’re investing in skin that stays resilient for years to come. Skincare devices like NIRA make it easier than ever to keep your collagen production active, all from the comfort of your home. Whether you’re just noticing the first signs of aging or looking to enhance your current routine, now’s the perfect time to take action.
Learn more
Saggy Skin: Why Your Skin Is Sagging and What Actually Helps
TL;DR Facial sagging stems from collagen/elastin decline, fat-pad descent, and UV/lifestyle stressors-topicals alone rarely reach the dermis to rebuild structure. Firmer skin comes from collagen-stimulating treatments (e.g., NIRA's 1450 nm non-fractional laser) used consistently-twice daily can show visible improvement in ~10-12 weeks-supported by peptides, antioxidant serums, and daily SPF. Action plan: commit to a NIRA routine, layer peptide/antioxidant skincare, and protect with sunscreen to slow breakdown and maintain results. Seeing changes in your skin’s firmness can feel unsettling. As early as our thirties, many begin noticing a shift in facial contours, particularly around the mouth, cheeks, and jawline. These visible signs are natural, but understanding why they occur opens the door to effective, safe solutions. With the right knowledge, you can address the underlying causes of sagging and restore a firmer, more youthful appearance over time. What Causes Facial Sagging as We Age Facial sagging develops gradually through a combination of internal structural changes and external influences. As early as our twenties, the production of collagen and elastin — proteins essential for strength and elasticity — begins to decline. This gradual reduction weakens the skin’s ability to maintain firmness and resilience. Skin laxity, or the loss of firmness and structure, becomes more apparent as natural moisture levels decrease, resulting in a thinner, less supple texture that is more vulnerable to environmental stressors.. Ultraviolet radiation accelerates collagen degradation, while lifestyle factors such as smoking, poor nutrition, and inconsistent sleep further compromise the skin’s integrity. Over time, the redistribution and downward shift of facial fat pads, compounded by gravity, create visible sagging, particularly around the cheeks, jawline, and mouth. Why Over-the-Counter Solutions Often Fall Short Many topical treatments claim to lift or firm the skin. While quality skincare can support hydration and provide antioxidant protection, most topical products do not penetrate deeply enough to stimulate significant collagen remodeling. Without targeted stimulation of collagen production within the dermis, lasting firmness remains elusive. What Actually Supports Firmer Skin Effectively addressing sagging skin requires treatments that reach the deeper layers where structural changes take place. NIRA’s non-fractional laser technology delivers controlled laser energy into the dermis, gently warming tissues below the pain threshold to stimulate the skin’s natural collagen renewal process. Alongside advanced technology, incorporating skincare products enriched with peptides further supports firmness and resilience, as these short chains of amino acids act as essential building blocks for proteins like collagen. Protecting the skin with consistent use of sunscreen and antioxidant serums is equally important to defend against ongoing collagen degradation caused by ultraviolet exposure and environmental free radicals. Hydrating adequately, consuming nutrient-dense foods rich in vitamins A, C, and E, maintaining regular physical activity, and prioritizing quality sleep all contribute to healthier skin from within. For individuals seeking additional support, in-office procedures such as microneedling, ultrasound therapies, and clinical laser treatments can complement a consistent at-home regimen. Supporting Skin Firmness at Home Clinically proven, non-fractional laser technology is now available for safe and effective at-home use through NIRA devices. Developed with collaboration from dermatologists and engineered by specialists in laser technology, NIRA offers results that are comparable to certain in-office treatments, without the inconvenience, discomfort, or extended recovery periods. NIRA’s non-fractional laser emits light at a wavelength of 1450 nanometers, carefully targeting the dermis to stimulate collagen renewal while preserving the integrity of the skin’s surface. With short, consistent treatments performed twice daily, users often begin to observe gradual, visible improvements in skin firmness within 10 to 12 weeks. The device gently warms the dermal layers without exceeding pain thresholds, creating a comfortable and seamless addition to a daily skincare routine. How the NIRA Skincare System Complements Treatment NIRA’s Ultimate Bundle+ offers a complete approach to skin renewal by combining the collagen-stimulating effects of its non-fractional laser technology with anti-aging skincare products, optimizing results through consistent, targeted care. NIRA is the only at-home device clinically proven to reduce fine lines and wrinkles around the eyes, an area particularly susceptible to early signs of sagging due to its delicate structure. Clinical results are specific to the periocular area, underscoring the precision and efficacy of the treatment. Designed for ease of use, the device integrates seamlessly into a daily skincare regimen, supporting long-term skin health with minimal disruption to existing routines. For a deeper understanding of how combining peptides and laser technology enhances skin rejuvenation, additional information is available here. Addressing the Neck and Jawline While much focus is placed on facial sagging, the neck and jawline are equally important for maintaining a cohesive, youthful appearance. The skin in these areas is often thinner and more vulnerable to gravitational changes. Apply NIRA treatments and skincare to the neck and jawline consistently, following the natural contours of the face to ensure even results. Discover more tips on caring for the neck and décolletage here. You Can Do Something About Sagging Skin Sagging skin is a natural part of aging, but effective, science-backed solutions are available. By prioritizing collagen stimulation, protecting the skin from further damage, and committing to consistent care, firmer, more resilient skin is within reach. NIRA provides a dermatologist-informed, pain-free solution for those who seek either natural, at-home options or a professional-grade maintenance plan between office visits. NIRA remains dedicated to supporting skin health through proven, accessible technology. Frequently Asked Questions Can I effectively firm my face at home? Yes. Devices like NIRA’s at-home lasers use clinically validated technology to safely stimulate natural collagen production within the skin’s dermis. How long does it take to see results? With consistent, twice-daily use, many users report seeing visible improvements within 10 to 12 weeks. What is the most effective treatment for sagging jowls? Collagen stimulation, combined with targeted skincare and sun protection, provides one of the most reliable approaches to improving firmness in the jowl area. Do collagen supplements or creams help? While collagen supplements and topical creams support overall skin health, stimulating natural collagen production within the dermis yields the most visible, lasting results.
Learn more